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Gut Health

Plexus VitalBiome™

This revolutionary probiotic supplement helps balance your gut microbiome with ingredients that help improve your health and your mood! Its exceptional formula delivers diverse probiotic strains that help reduce occasional GI discomfort and rebalance your gut microflora, while promoting healthy digestion.*The award-winning Plexus VitalBiome® was made a Best Probiotic Finalist at the 2026 Get the Gloss Wellness Awards.

60-day money-back guarantee · Shipping is calculated at checkout.

Plexus VitalBiome™$51.00

what it does.

This revolutionary probiotic supplement helps balance your gut microbiome with ingredients that help improve your health and your mood! Its exceptional formula delivers diverse probiotic strains that help reduce occasional GI discomfort and rebalance your gut microflora, while promoting healthy digestion.*

The award-winning Plexus VitalBiome® was made a Best Probiotic Finalist at the 2026 Get the Gloss Wellness Awards.

  • Helps reduce feelings of stress, nervousness, and tension*
  • Stabilizes stress hormones and promotes relaxation*
  • Supports balanced cortisol levels*
  • Helps reduce occasional gastrointestinal discomfort*
  • Supports a healthy immune system*

Features

  • 7 billion CFU
  • 8 clinically researched strains, including 2 psychobiotic strains
  • Delayed-release capsules
  • Gluten free, vegetarian, and non-GMO
  • No artificial colors

what's in it.

Lactobacillus helveticus (Rosell-52) — A probiotic strain that helps enhance gut microbiome health, improve mood, and reduce feelings of stress and tension.*

Bacillus coagulans (MTCC 5856) LactoSpore® — A probiotic strain that has been demonstrated by 11 clinical studies to reduce occasional gastrointestinal discomfort and benefit health.*

Bifidobacterium longum (Rosell-175) — A probiotic strain that is clinically shown to support mood and relaxation and help reduce stress-induced digestive discomfort when combined with L. helveticus (Rosell-52).*

Saccharomyces boulardii — A gut-healthy probiotic yeast that helps support intestinal yeast balance and gut lining.*

◊The results of an in-vitro human gut simulator study suggest that VitalBiome's formula may have several beneficial effects. Further research, including research conducted in humans, is needed to confirm these preliminary findings.

The full supplement facts label is the second image in the gallery.

how to use.

Adults take 1 capsule daily.

the evidence.

The benefit statements on this page are Plexus’s own, word for word, and each one carries the FDA disclaimer below.

How we label evidence

questions.

What if it is not for me?

You have 60 days to change your mind. Read the guarantee.

What does VIP cost, and when does it renew?

VIP membership is $9.95 to join (usually $19.95), then $19.95 a year. It saves up to 25% on products that show a VIP price. You will see the renewal date before you pay, and the fee is covered by the 60-day guarantee.

Can I get this every month?

Yes. Tick “Also deliver this every month” before you add it. It is never ticked for you.

More questions

See all questions, or ask your Brand Ambassador.

warnings.

Read the full product label, including any warnings, before use. The label is in the image gallery above.

If you are pregnant, nursing, taking medication or have a medical condition, talk to your healthcare provider before using this product. Keep out of reach of children.

seen in real kitchens.

Brand Ambassadors and customers showing how Plexus fits into an ordinary day.

  1. ♢In vitro, preliminary. The results of an in vitro human gut simulator study suggest that Slim’s formula may have several beneficial effects. Further research, including research conducted in humans, is needed to confirm these preliminary findings.↩
  2. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.↩