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Science

what we can show you.

How the Gut Health System is meant to work, which studies sit behind it, and how each one is labelled, so you always know what kind of evidence you are reading.

Every claim on this page is labelled

  • In vitro, preliminary
  • Clinically studied ingredient
  • Patent
See how it works How we label evidence
A glass of Slim Microbiome Activating mixed with water, beside its packet
PlexusFounded in gut health. Experts in microbiome.
The Gut Health System
weed, seed, feed.
U.S. Patent, Slim Microbiome Activating
No. 11730749
By FDA cGMP manufacturers
made in the USA
Accredited labs do the testing
ISO 17025

01 · How it works

3 steps to a balanced microbiome.*

Plexus teaches the Gut Health System as three steps: weed, seed, feed. Each step is its own product, and each product page lists Plexus’s own benefit statements, word for word.

  1. weed.

    Bio Cleanse

    Digestive support through cleansing.*

    • Helps cleanse the gastrointestinal tract*
    • Helps promote regularity*
    What’s inside
    Magnesium
    Essential mineral to the body.
    Vitamin C
    Provides antioxidant support.*
    Citrus bioflavonoids
    Hesperidin (from orange), orange peel powder, lemon peel powder, and quince fruit powder.
    See Bio Cleanse

  2. seed.

    ProBio 5

    Restore balance to your gut.*

    • Helps keep intestinal yeast in balance*
    • Supports healthy digestion*
    What’s inside
    5 beneficial probiotics
    Lactobacillus acidophilus, Bifidobacterium longum, Lactobacillus plantarum, Bacillus coagulans and Saccharomyces boulardii.
    Enzyme blend
    Made up of proteases, cellulase, and serrapeptase, this enzyme blend helps break down proteins, peptides, and cellulose fiber from plants to support healthy digestion and improve nutrient absorption.*
    2 billion CFU
    Per capsule, at time of manufacture.
    See ProBio 5

  3. feed.

    Slim Microbiome Activating

    Feed your gut. Flourish with health.*

    • Promotes the growth of beneficial gut microbes*
    • Clinically studied XOS prebiotic
    What’s inside
    Xylooligosaccharides (XOS)
    A clinically studied prebiotic. See chapter 04 below.
    Green coffee bean extract
    Chromium polynicotinate
    See Slim Microbiome Activating
See the Gut Health System

02 · Evidence types

know what you’re reading.

Every study and claim on this page carries a label that says what kind of evidence it is. Here is what each label means.

  • In vitro, preliminary

    Work done in a lab model, not in people. It is marked ♢ and always comes with Plexus’s note that more research, including research in humans, is needed.

  • Clinically studied ingredient

    An ingredient that has been looked at in clinical research. The label describes the ingredient, not a study of the finished product.

  • Patent

    A patent describes a formula. It is a legal record, not a study of results.

In vitro, preliminary

slim in a gut simulator.

Slim Microbiome Activating in Black Cherry Lime Blossom
In vitro, preliminary

Slim Microbiome Activating’s formula was looked at in an in vitro human gut simulator: a lab model of the gut, not a study in people. These are Plexus’s own statements from that work, word for word.

  • Plexus statement · In vitro, preliminary

    Increases Lactobacillus up to 365 times and Bifidobacterium up to 290 times — contributing to overall health♢*

  • Plexus statement · In vitro, preliminary

    Increases the metabolism-enhancing Akkermansia microbes up to 250 times♢*

♢The results of an in vitro human gut simulator study suggest that Slim’s formula may have several beneficial effects. Further research, including research conducted in humans, is needed to confirm these preliminary findings.

See Slim Microbiome Activating

Clinically studied ingredient

a clinically studied prebiotic.

Slim Microbiome Activating is made with xylooligosaccharides (XOS), a clinically studied prebiotic. Here is what Plexus says about XOS and the formula’s two other key ingredients, word for word.

Read the full Slim label

  • Clinically studied ingredient

    Xylooligosaccharides (XOS)

    Clinically demonstrated prebiotic that feeds beneficial microbes.*

    In Slim Microbiome Activating

  • Key ingredient

    Green coffee bean extract

    Naturally derived extract that can help decrease the absorption of sugars and thereby supports a healthy glucose metabolism.*

    In Slim Microbiome Activating

  • Key ingredient

    Chromium polynicotinate

    Essential trace mineral that assists with the transportation of glucose into cells.*

    In Slim Microbiome Activating

Patent

a patented formula.

U.S. Patent

No. 11730749

  • Patented formula for improving gut health (U.S. Patent No. 11730749)

Slim Microbiome Activating

Slim Microbiome Activating, Raspberry Lemon Watermelon bag

Slim Microbiome Activating’s formula is patented. This is Plexus’s statement, word for word.

A patent describes a formula. It is a legal record, not a study of results.

See Slim Microbiome Activating
A bottle of ProBio 5 capsules
Made in the USA

06 · Quality

made in the usa. tested by accredited labs.

What happens between the formula and your kitchen counter, in Plexus’s own facts.

  1. Formulated

    by a product innovation team.

    Plexus products are developed by its product innovation team, led by RenHau Lai, VP, Product Innovation.

  2. Made

    in the USA.

    Made by FDA cGMP manufacturers.

  3. Tested

    by accredited labs.

    Tested by ISO 17025 accredited labs.

  4. Held to a code

    by industry associations.

    Plexus is a member of the Council for Responsible Nutrition and the U.S. Direct Selling Association, and abides by the DSA Code of Ethics.

  5. Backed

    by a 60-day money-back guarantee.

    If a product isn’t right for you, the guarantee page explains how returns work.

    Read the guarantee

07 · Labels

read the label.

Every product page shows the full product label. Read it, including the directions and any warnings, before you start.

If you are pregnant, nursing, taking medication or have a medical condition, talk to your healthcare provider first.

Start here

good things begin within.

The Gut Health System puts all three steps in one routine: Bio Cleanse, ProBio 5 and Slim Microbiome Activating.

See the Gut Health System Find my routine

Every Plexus product comes with a 60-day money-back guarantee.

  1. ♢In vitro, preliminary. The results of an in vitro human gut simulator study suggest that Slim’s formula may have several beneficial effects. Further research, including research conducted in humans, is needed to confirm these preliminary findings.↩
  2. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.↩